Coating system
Enteric Coating System
Ready-mix enteric coating material on four polymer bases, each grade formulated for a named active rather than sold as a single universal film.
- 5 gradesEach with its own data sheet
- Aqueous and solventProcess base
- Parameters by pan sizePublished below
- WHO-GMP unitMade at Tahliwal, Una
What this range covers
Rglax Coat enteric coating products help you deliver a final tablet that saves development, scale-up and production time, while assuring the integrity of the coating for the safety and efficacy of your finished dosage form. Systems are available on a variety of delayed release polymers for aqueous or organic processing.
Actives covered by grades in this range
- Pantoprazole group
- Diclofenac
- Serratiopeptidase
- Duloxetine
- Mesalamine
Range
- Grades held
- 5
- Process base
- Non-aqueous (solvent), Aqueous
- Brand
- Rglax Coat
- Made at
- Tahliwal, Distt. Una, H.P.
Grades in this range
5 grades, each with its own data sheet.
ECM-RP347Enteric coat, methacrylic base, non-aqueousSolvent base methacrylic enteric film for the Pantoprazole group.For Pantoprazole group
ECM-RP348Enteric coat, methacrylic base, aqueousWater base methacrylic enteric film for Diclofenac and Serratiopeptidase.For Diclofenac, Serratiopeptidase
ECPT5Enteric coat, phthalate basePhthalate base enteric system for Duloxetine enteric tablets.For Duloxetine
ECMSEnteric coat, methacrylic second bondSecond bond methacrylic enteric system for Mesalamine.For Mesalamine
EC714Enteric coat, CAP baseCellulose acetate phthalate enteric film for Diclofenac and Serratiopeptidase.For Diclofenac, Serratiopeptidase
Application parameters
Starting parameters by pan size.
| Parameter | Conventional coater12 inch pan | Auto coater24 inch pan | Conventional coater36 inch pan | Auto coater48 inch pan |
|---|---|---|---|---|
| Pan speed (rpm) | 18 to 20 | 10 to 14 | 8 to 12 | 3 to 5 |
| Tablet charge (kg) | 0.5 to 1 | 3 to 5 | 40 to 50 | 100 to 130 |
| Tablet bed temp (°C) | 30 to 32 | 30 to 32 | 30 to 32 | 30 to 32 |
| Inlet temp (°C) | 45 to 50 | 45 to 50 | 45 to 50 | 45 to 50 |
Temperatures given as aqueous / non-aqueous · indicative, confirmed against your core at trial
The chemistry behind it
- Methacrylic acid copolymerA methacrylic film is insoluble while the surrounding pH stays low and dissolves once it rises. That pH dependence is the whole mechanism. Nothing about the film is doing timed release, it simply waits for the environment to change.
- Cellulose acetate phthalateCAP is an ester that stays intact in acid and hydrolyses as pH rises. The result is the same gastro resistance as a methacrylic film, reached by a different chemistry.
- Phthalate base polymerA phthalate base gives a delayed release film whose dissolution behaviour differs from a methacrylic one even where both are described as enteric. The release point is governed by the polymer rather than by the build-up.
Before you specify a grade
Other coating systems
- Film coatingAqueous and non-aqueous film coats, formulated to your application and regulatory requirement.
- Moisture barrierHPMC and PVA based immediate release systems that protect against light, moisture and environmental gases.
- Seal and pre-coatTransparent and coloured sub-coats that prepare the core for enteric or functional layers.
- Sugar coatingFully formulated HPMC sucrose based systems for a classic sugar coated finish.
- Metallic and pearlNon-aqueous metallic and pearl effect film coats, shade matched to your reference sample.
- Sustained releaseControlled release drug delivery blends for extended release solid dosage forms.
- Taste maskMasking the taste and odour of bitter actives in suspensions and dispersibles.
- DissolutionDissolution enhancer blends for disintegration time and dissolution correction.
- Hygroscopic adsorbentAdsorbent material for hygroscopic drugs that create problems during and after compression.
Need help choosing a grade
Talk to our technical team.
Send the core composition, the shade reference and the coater you will run it on, and we will tell you which enteric coating grade we would put on it.
From lab scale to commercial supply.