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Rglax Pharma

Process tool

Tablet coating weight gain calculator

How much dry coating material a batch needs at a target percentage weight gain, including process loss.

  • Runs in the browserNothing is submitted anywhere
  • Working shownCheck every line by hand
  • Plant figuresThe bands our grades run in
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Written by the Rglax Pharma technical team, who formulate and manufacture every grade named on this calculator at our WHO-GMP works in Tahliwal, Una (drug manufacturing licence NNZ/23/238). Reviewed 3 September 2026. Licences and certificates.

Coated tablets on a laboratory balance pan

Your batch

Core weight loaded into the pan

2 to 4% film, 6 to 12% enteric

Spray drying and pan loss, usually 10 to 20%

Result

Material to issue

1.553 kg

Includes 15% process loss

Dry coating applied
1.35 kgWhat ends up on the tablets
Tablets in the charge
90,000
Coating per tablet
15 mg
Coated tablet weight
515 mg

How this was worked out

  1. dry coating = 45 kg × 3% ÷ 100 = 1.35 kg
  2. material to issue = 1.35 kg × (1 + 15 ÷ 100) = 1.553 kg
  3. tablets = 45 kg ÷ 500 mg = 90,000
  4. per tablet = 1.35 kg ÷ 90,000 = 15 mg

Formula

dry coating (kg) = charge (kg) × weight gain (%) ÷ 100
material to issue = dry coating × (1 + process loss ÷ 100)

Why this number matters

Weight gain is how a coating run is specified and how it is signed off. You weigh the charge in, coat until the tablets have picked up the target percentage, and stop. Everything else, spray rate, pan speed, bed temperature, exists to get you there without a defect. The figure that matters on the shop floor is the second one, because you have to issue more material than ends up on the tablet.

Where it goes wrong

Process loss varies with pan design, spray gun setup and how well the run is controlled. Fifteen percent is a reasonable planning figure for a first trial, and your own runs will give you a better one within two or three batches.

Worked example

With tablet charge of 45 kg, target weight gain of 3 %, process loss of 15 % and core weight of 500 mg, the calculation gives:

Dry coating appliedWhat ends up on the tablets
1.35 kg
Material to issueIncludes 15% process loss
1.553 kg
Tablets in the charge
90,000
Coating per tablet
15 mg
Coated tablet weight
515 mg

The arithmetic is 2 lines, shown beside the result above so it can be checked by hand: dry coating (kg) = charge (kg) × weight gain (%) ÷ 100; material to issue = dry coating × (1 + process loss ÷ 100).

Typical ranges

  • Tablet charge(kg)Core weight loaded into the pan
  • Target weight gain(%)2 to 4% film, 6 to 12% enteric
  • Process loss(%)Spray drying and pan loss, usually 10 to 20%

These are the bands our grades were developed in at Tahliwal. A run outside them is not wrong, but it is a run the published parameters no longer describe.

Typical weight gain by application

General guidelines. They vary with the formulation, the process and the finish you are after.

ApplicationTypical weight gain
Film coating (standard)2 – 5%
Film coating (high opacity)5 – 8%
Enteric coating8 – 15%
Moisture barrier coating3 – 8%
Sugar coating20 – 60%
Seal and pre-coat1 – 3%
Taste mask coating3 – 8%
Sustained release coating5 – 15%
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Other calculators

Every grade page carries the process parameters it was developed on, so you can start from a known point rather than a calculated one. Browse the grades.

Need a second opinion

Talk to our technical team.

Send the core, the coater and the target and we will tell you what we would run, and which grade we would run it with.

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