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Rglax Pharma

Process tool

Coating dispersion and solids calculator

Water or solvent needed to disperse a ready-mix powder at a given solids concentration.

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  • Working shownCheck every line by hand
  • Plant figuresThe bands our grades run in
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Written by the Rglax Pharma technical team, who formulate and manufacture every grade named on this calculator at our WHO-GMP works in Tahliwal, Una (drug manufacturing licence NNZ/23/238). Reviewed 3 September 2026. Licences and certificates.

A stainless dispersion vessel holding milky coating dispersion

Your batch

From the weight gain calculator

12 to 20% aqueous, 5 to 12% solvent

1.00 water, about 0.79 IPA

Result

Total dispersion

10.333 kg

Vehicle to add
8.783 kgPurified water or solvent
Vehicle volume
8,783 ml
Dispersion ratio
1 : 5.67powder to vehicle by weight

How this was worked out

  1. total dispersion = 1.55 kg ÷ (15 ÷ 100) = 10.333 kg
  2. vehicle = 10.333 − 1.55 = 8.783 kg
  3. volume = 8.783 kg × 1000 ÷ 1 = 8,783 ml

Formula

total dispersion (kg) = powder (kg) ÷ (solids % ÷ 100)
vehicle = total dispersion − powder

Why this number matters

A ready-mix grade is supplied dry and dispersed on your side. The solids concentration you choose is a trade. Higher solids means less water to evaporate and a shorter run, but a thicker dispersion that is harder to pump and easier to block a gun with. Lower solids sprays cleanly and takes longer. Most aqueous work sits between 12 and 20 percent.

Where it goes wrong

Disperse under moderate shear and let the dispersion stand long enough for entrapped air to come out before spraying. Air in the line reads as spitting at the gun and shows up on the tablets as spray marks.

Worked example

With coating powder of 1.55 kg, solids concentration of 15 % w/w and vehicle density of 1 g/ml, the calculation gives:

Total dispersion
10.333 kg
Vehicle to addPurified water or solvent
8.783 kg
Vehicle volume
8,783 ml
Dispersion ratiopowder to vehicle by weight
1 : 5.67

The arithmetic is 2 lines, shown beside the result above so it can be checked by hand: total dispersion (kg) = powder (kg) ÷ (solids % ÷ 100); vehicle = total dispersion − powder.

Typical ranges

  • Coating powder(kg)From the weight gain calculator
  • Solids concentration(% w/w)12 to 20% aqueous, 5 to 12% solvent
  • Vehicle density(g/ml)1.00 water, about 0.79 IPA

These are the bands our grades were developed in at Tahliwal. A run outside them is not wrong, but it is a run the published parameters no longer describe.

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Every grade page carries the process parameters it was developed on, so you can start from a known point rather than a calculated one. Browse the grades.

Need a second opinion

Talk to our technical team.

Send the core, the coater and the target and we will tell you what we would run, and which grade we would run it with.

From the calculation to the pan.

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