ECMS

Enteric coat, methacrylic second bond

Second bond methacrylic enteric system for Mesalamine.

Written by the Rglax Pharma technical team, who formulate and manufacture every grade named on this grade page at our WHO-GMP works in Tahliwal, Una (drug manufacturing licence NNZ/23/238). Reviewed 3 September 2026. Licences and certificates.

₹1,300per kg, indicativeGet a quote

Product details

Product code: ECMS
Brand: Rglax Coat
Coating system: Enteric Coating System
Process base: Non-aqueous (solvent)
Finish: Enteric film, delayed release
Physical form: Ready-mix powder, dispersed on site
Usage: Pharmaceutical, nutraceutical, ayurvedic and herbal solid dosage
Made at: Plot No. 30, Industrial Area Tahliwal, Himachal Pradesh, India

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ECMS price and quantity

Indicative price: ₹1,300 per kg
Trial quantity: Sent before any commercial order
Shade matching: Against a retained sample you send us
Supplied as: Ready-mix powder, dispersed on site
Quoted against: Shade, pack size and annual volume

ECMS product specifications

Coating system: Enteric Coating System
Process base: Non-aqueous (solvent)
Finish: Enteric film, delayed release
Supply form: Ready-mix
Actives named: Mesalamine
Shade matching: Against your retained sample

ECMS trade information

Despatched from: Plot No. 30, Industrial Area Tahliwal, Himachal Pradesh, India
Supplied to: India and export markets
Licence: NNZ/23/238
Compliance: WHO-GMP Compliance Unit

Price and minimum order

We do not publish a rate for ECMS because it moves with the shade, the pack size and the annual volume, and a number that ignores those three is a number you would have to renegotiate. Send the tablet, the target and the quantity and you get a firm quote the same working day.

A trial quantity goes out before any commercial order, with the process parameters this grade was developed on, so you can run it on your own pan before anyone commits to anything.

What to send us

The active and the strength
A retained tablet, if you are matching a shade
Coater size and batch charge
Target release profile or stability zone
Approximate annual quantity

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Product description

Methacrylic base enteric coating on a second bond, formulated for Mesalamine enteric tablets where release has to be held until a defined point in the intestinal tract.

Hold the cool enteric band through the whole stage. The second bond is doing the work of holding release until a defined point in the tract, so dissolution testing rather than appearance is what tells you the coat is right.

Polymers in this film

Methacrylic acid copolymerA methacrylic film is insoluble while the surrounding pH stays low and dissolves once it rises. That pH dependence is the whole mechanism. Nothing about the film is doing timed release, it simply waits for the environment to change.

Recommended process

The parameters this grade was developed on, so your first trial starts from a known point.

Units

Starting process parameters by pan size
Parameter	Conventional coater12 inch pan	Auto coater24 inch pan	Conventional coater36 inch pan	Auto coater48 inch pan
Pan speed (rpm)	18 to 20	10 to 14	8 to 12	3 to 5
Tablet charge (kg)	0.5 to 1	3 to 5	40 to 50	100 to 130
Tablet bed temp (°C)	30 to 32	30 to 32	30 to 32	30 to 32
Inlet temp (°C)	45 to 50	45 to 50	45 to 50	45 to 50

Temperatures given as aqueous / non-aqueous · indicative, confirmed against your core at trial

Work out the quantity for your batchHow much ECMS to issue at your charge and target weight gain.Set the spray rateGrams per minute per gun from your dispersion quantity and process window.

FAQs about ECMS

The second bond holds release until a defined point in the intestinal tract, which is what Mesalamine needs. A standard gastro resistant film releases too early for that product.

By dissolution testing rather than appearance. A Mesalamine coat that looks correct can still release at the wrong point, so the dissolution profile is the acceptance criterion.

Tell us your requirement

Name the tablet, the target and the volume. We quote against ECMS or against whichever grade actually fits, and we will say so if it is a different one.

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ECMS

Enteric coat, methacrylic second bond

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